Article
Conservation and diversity in the immunity regions of wild phages with the immunity specificity of phage lambda.
Molecular microbiology - 1 Apr 2007
Degnan Patrick H, Michalowski Christine B, Babić Andrea C, Cordes Matthew H J, Little John W
Abstract excerpt
The gene regulatory circuitry of phage lambda is among the best-understood circuits. Much of the circuitry centres around the immunity region, which includes genes for two repressors, CI and Cro, and their cis-acting sites. Related phages, termed lambdoid phages, have different immunity regions, but similar regulatory circuitry and genome organization to that of lambda, and show a mosaic organization, arising by...
Topics
- Bacteriophage lambda
- Bacteriophages
- Base Sequence
- Conserved Sequence
- DNA-Binding Proteins
- Gene Expression Regulation, Viral
- Genetic Variation
- Lysogeny
- Molecular Sequence Data
- Operator Regions, Genetic
- Repressor Proteins
- Sequence Analysis, DNA
- Viral Proteins