Article
Pollen tetrad-based visual assay for meiotic recombination in Arabidopsis.
Proceedings of the National Academy of Sciences of the United States of America - 6 Mar 2007
Francis Kirk E, Lam Sandy Y, Harrison Benjamin D, Bey Alexandra L, Berchowitz Luke E, Copenhaver Gregory P
Abstract excerpt
Recombination, in the form of cross-overs (COs) and gene conversion (GC), is a highly conserved feature of meiosis from fungi to mammals. Recombination helps ensure chromosome segregation and promotes allelic diversity. Lesions in the recombination machinery are often catastrophic for meiosis, resulting in sterility. We have developed a visual assay capable of detecting Cos and GCs and measuring CO interference...
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