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Article

XRCC1 Arg194Trp polymorphism, risk of nonmelanoma skin cancer and extramammary Paget's disease in a Japanese population.

Archives of dermatological research - 1 Jul 2012

Chiyomaru Koji, Nagano Tohru, Nishigori Chikako

Abstract excerpt

The X-ray repair cross-complementing groups 1 gene plays an important role in base excision repair. At least three common single nucleotide polymorphisms frequently occur in this gene (Arg399Gln, Arg194Trp and Arg280His). Recent studies reported that these polymorphisms were associated with not only risk of visceral malignancy but also that of skin cancer such as basal cell carcinoma and squamous cell carcinoma,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22639094
DOI: 10.1007/s00403-012-1245-1
PMCID: PMC3382288

Genes

XRCC1

Provenance

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