Article
Microevolution in genomic short sequence repeats of Candida albicans in non-neutropenic patients.
Yeast (Chichester, England) - 1 Mar 2007
Al-Aidan Al Waleed, Goessens Wil, Lemmens-den Toom Nicole, Al-Ahdal Mohammed, van Belkum Alex
Abstract excerpt
The genome of the yeast Candida albicans harbours many genomic short sequence repeats (SSRs). These are stable upon transition of colonization to infection in immune-compromised patients. We show here that in non-neutropenic patients this transition may coincide with variation in several of the SSRs. This may have implications for stage-specific expression of C. albicans pathogenicity factors.
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