Article
Insertion/deletion polymorphism and serum activity of the angiotensin-converting enzyme in Turkish patients with obstructive sleep apnea syndrome.
Biochemical genetics - 1 Jun 2010
Ogus Candan, Ket Serap, Bilgen Turker, Keser Ibrahim, Cilli Aykut, Gocmen Ayse Yesim, Tosun Ozgur, Gumuslu Saadet
Abstract excerpt
This study determined the allelic frequency and genotypic distribution of an angiotensin-converting enzyme (ACE) polymorphism and serum ACE activity in Turkish patients with obstructive sleep apnea syndrome (OSAS). A colorimetric assay measured serum ACE activity in 73 of 97 subjects. Frequencies for II, ID, and DD genotypes were 19.6, 53.6, and 26.8% in the OSAS group and 15, 38, and 47% in the control group,...
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