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Article

Yeast RHO3 and RHO4 ras superfamily genes are necessary for bud growth, and their defect is suppressed by a high dose of bud formation genes CDC42 and BEM1.

Molecular and cellular biology - 1 Dec 1992

Matsui Y, Toh-E A

Abstract excerpt

RHO3 and RHO4 are members of the ras superfamily genes of the yeast Saccharomyces cerevisiae and are related functionally to each other. Experiments using a conditionally expressed allele of RHO4 revealed that depletion of both the RHO3 and RHO4 gene products resulted in lysis of cells with a small bud, which could be prevented by the presence of osmotic stabilizing agents in the medium. rho3 rho4 cells incubated...

Topics

Adaptor Proteins, Signal Transducing
Cell Polarity
Fungal Proteins
Genes, Fungal
Genes, ras
Kinetics
Multigene Family
Phenotype
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Suppression, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transformation, Genetic

cdc42 GTP-Binding Protein, Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 1448099
DOI: 10.1128/mcb.12.12.5690-5699.1992
PMCID: PMC360509

Genes

CDC42

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1448099-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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