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Article

Yeast RHO3 and RHO4 ras superfamily genes are necessary for bud growth, and their defect is suppressed by a high dose of bud formation genes CDC42 and BEM1.

Molecular and cellular biology - 1 Dec 1992

Matsui Y, Toh-E A

Abstract excerpt

RHO3 and RHO4 are members of the ras superfamily genes of the yeast Saccharomyces cerevisiae and are related functionally to each other. Experiments using a conditionally expressed allele of RHO4 revealed that depletion of both the RHO3 and RHO4 gene products resulted in lysis of cells with a small bud, which could be prevented by the presence of osmotic stabilizing agents in the medium. rho3 rho4 cells incubated...

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Source

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Identifiers

PMID: 1448099
DOI: 10.1128/mcb.12.12.5690-5699.1992
PMCID: PMC360509

Genes

CDC42

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Source receipt: pubmed, retrieved 7 Sept 2026.

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