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Article

Mechanisms of disease: pharmacogenetics of testosterone therapy in hypogonadal men.

Nature clinical practice. Urology - 1 Mar 2007

Zitzmann Michael

Abstract excerpt

A defective, mutated androgen receptor may lead to variable phenotypes of androgen insensitivity in humans. Also, the CAG repeat polymorphism in exon 1 of the androgen receptor gene modulates androgen effects; in vitro, transcription of androgen-dependent target genes is attenuated with increasing length of triplet residues. Clinically, the CAG repeat polymorphism causes significant modulations of androgenicity...

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Share to Androgens
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Share to Hypogonadism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

Share to Receptors, Androgen

Share to Testosterone

Share to Treatment Outcome

Source

Identifiers

PMID: 17347661
DOI: 10.1038/ncpuro0706

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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