Article
Relationship between metabolic syndrome and Trp64arg polymorphism of the beta-adrenergic receptor gene in a general sample: the Shigaraki study.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Nov 2006
Tamaki Shinji, Nakamura Yasuyuki, Tabara Yasuharu, Okamura Tomonori, Kita Yoshikuni, Kadowaki Takashi, Tsujita Yasuyuki, Horie Minoru, Miki Tetsuro, Ueshima Hirotsugu
Abstract excerpt
It has been reported that the beta3-adrenergic receptor gene (ADRB3) is associated with abnormal metabolic risk factors. Therefore, we examined whether the Trp64Arg polymorphism of ADRB3 affects the occurrence of metabolic syndrome (MS). The participants were 2,395 subjects who underwent a medical examination in Shigaraki in Shiga, Japan. Among them, 1,416 subjects who gave informed consent for genetic analysis...
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