Article
Myotonic dystrophy: clinical assessment of muscular disability in an isolated population with presumed homogeneous mutation.
Neurology - 1 Jan 1992
Mathieu J, De Braekeleer M, Prévost C, Boily C
Abstract excerpt
We evaluated the muscular disability of 295 patients affected by the adult form of myotonic dystrophy (DM) and living in the Saguenay-Lac-Saint-Jean region (Quebec, Canada). The patients are known to have a common ancestral couple, and a homogeneous DM mutation is presumed. Using a five-point muscular disability rating scale (MDRS), we confirmed, in each age group, the wide expressivity of the muscular...
Topics
- Adolescent
- Adult
- Aged
- Aging
- Child
- Disability Evaluation
- Female
- Humans
- Male
- Middle Aged
- Muscles
- Mutation
- Myotonic Dystrophy