Article
The pharmacogenetics research network: from SNP discovery to clinical drug response.
Clinical pharmacology and therapeutics - 1 Mar 2007
Giacomini K M, Brett C M, Altman R B, Benowitz N L, Dolan M E, Flockhart D A, Johnson J A, Hayes D F, Klein T, Krauss R M, Kroetz D L, McLeod H L, Nguyen A T, Ratain M J, Relling M V, Reus V, Roden D M, Schaefer C A, Shuldiner A R, Skaar T, Tantisira K, Tyndale R F, Wang L, Weinshilboum R M, Weiss S T, Zineh I
Abstract excerpt
The NIH Pharmacogenetics Research Network (PGRN) is a collaborative group of investigators with a wide range of research interests, but all attempting to correlate drug response with genetic variation. Several research groups concentrate on drugs used to treat specific medical disorders (asthma, depression, cardiovascular disease, addiction of nicotine, and cancer), whereas others are focused on specific groups...
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