Article
Haplotype-defined linkage region for gPRA in Schapendoes dogs.
Molecular vision - 7 Feb 2007
Lippmann Tanja, Jonkisz Anna, Dobosz Tadeusz, Petrasch-Parwez Elisabeth, Epplen Jorg T, Dekomien Gabriele
Abstract excerpt
PURPOSE: In order to determine the molecular basis of canine generalized progressive retinal atrophy (gPRA), we initiated whole-genome scanning for linkage in gPRA-informative pedigrees of the Schapendoes breed. METHODS: Detailed pedigree and ophthalmological data were assembled in selected Schapendoes pedigrees. A whole-genome scan was initiated by two-point linkage analysis using microsatellite markers in...
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