Article
MX1 exon 13 polymorphisms in broiler breeder chickens and associations with commercial traits.
Animal genetics - 1 Apr 2007
Livant E J, Avendano S, McLeod S, Ye X, Lamont S J, Dekkers J C M, Ewald S J
Abstract excerpt
The Mx1 gene in mice is induced by type I interferons and is the major determinant of resistance to influenza virus and related orthomyxoviruses. It has been previously shown that a SNP in exon 13 of the chicken MX1 gene determines differential antiviral activity of the protein. We evaluated this SNP and two additional SNPs in elite broiler lines by PCR amplification and sequence analysis. Associations between...
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