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Article

The MAT1 Locus of Histoplasma capsulatum Is Responsive in a Mating Type-Specific Manner

24 Feb 2007

Abstract excerpt

Recombination events associated with sexual replication in pathogens may generate new strains with altered virulence. Histoplasma capsulatum is a mating-competent, pathogenic fungus with two described phenotypic mating types, + and -. The mating (MAT) locus of H. capsulatum was identified to facilitate molecular studies of mating in this organism. Through syntenic analysis of the H. capsulatum genomic sequence...

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PMID: 17322347
DOI: 10.1128/ec.00020-07

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