Frequency and genetic diversity of the MAT1 locus of Histoplasma capsulatum isolates in Mexico and Brazil.

doi:10.1128/EC.00012-13

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Article

Frequency and genetic diversity of the MAT1 locus of Histoplasma capsulatum isolates in Mexico and Brazil.

Eukaryotic cell - 1 Jul 2013

Rodríguez-Arellanes Gabriela, Nascimento de Sousa Carolina, de Medeiros-Muniz Mauro, Ramírez José A, Pizzini Cláudia V, de Abreu-Almeida Marcos, Evangelista de Oliveira Manoel M, Fusco-Almeida Ana-Marisa, Vite-Garín Tania, Pitangui Nayla S, Estrada-Bárcenas Daniel A, González-González Antonio E, Mendes-Giannini María José Soares, Zancopé-Oliveira Rosely M, Taylor Maria-Lucia

Abstract excerpt

The MAT1-1 and MAT1-2 idiomorphs associated with the MAT1 locus of Histoplasma capsulatum were identified by PCR. A total of 28 fungal isolates, 6 isolates from human clinical samples and 22 isolates from environmental (infected bat and contaminated soil) samples, were studied. Among the 14 isolates from Mexico, 71.4% (95% confidence interval [95% CI], 48.3% to 94.5%) were of the MAT1-2 genotype, whereas 100% of...

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PMID: 23709181
DOI: 10.1128/EC.00012-13
PMCID: PMC3697462

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