Article
IL-10 genotype analysis in patients with Behçet's disease.
Human immunology - 1 Feb 2007
Wallace Graham R, Kondeatis Elly, Vaughan Robert W, Verity David H, Chen Yuanneng, Fortune Farida, Madanat Wafa, Kanawati Charlie A, Graham Elizabeth M, Stanford Miles R
Abstract excerpt
Behçet's disease (BD) is a multisystem inflammatory disease characterized by recurrent orogenital ulceration, ocular inflammation, and skin lesions. The etiology of the disease is currently unknown but evidence suggests that there is a strong genetic component mediating the chronicity of the disorder. We have examined the association between polymorphisms at position -1082, and -819 in the promoter region of the...
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