Article
Genome-wide scans for microalbuminuria in Mexican Americans: the San Antonio Family Heart Study.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Feb 2007
Arar Nedal, Nath Subrata, Thameem Farook, Bauer Richard, Voruganti Saroja, Comuzzie Anthony, Cole Shelley, Blangero John, MacCluer Jean, Abboud Hanna
Abstract excerpt
PURPOSE: Microalbuminuria, defined as urine albumin-to-creatinine ratio of 0.03 to 0.299 mg/mg, is a major risk factor for cardiovascular disease. Several genetic epidemiological studies have established that microalbuminuria clusters in families, suggesting a genetic predisposition. METHOD: We estimated heritability of microalbuminuria and performed a genome-wide linkage analysis to identify chromosomal regions...
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