Article
Frequency of CCR5 variants among rural populations with low HIV-1 prevalence in Cameroon.
AIDS (London, England) - 19 Feb 2007
Torimiro Judith N, Wolfe Nathan D, Thomas Alero, Martin Maureen P, Mpoudi-Ngole Eitel, Tamoufe Ubald, Birx Deborah L, Carrington Mary, Burke Donald S, Carr Jean K
Abstract excerpt
Among rural populations in Cameroon, HIV-1 prevalence is low and the genetic diversity broad. An unusual population-level genetic background may modulate this pattern of HIV infection. We examined HIV-1 prevalence, CCR5Delta32 and CCR5 promoter -2459 G genotype frequency among 1390 rural inhabitants. No individual was identified with the CCR5Delta32 allele, but homozygotes for the CCR5 promoter variant -2459G...
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