Article
Interleukin-1 beta-511 polymorphism and risk of cervical cancer.
Journal of Korean medical science - 1 Feb 2007
Kang Sokbom, Kim Jae Weon, Park Noh Hyun, Song Yong Sang, Park Sang Yoon, Kang Soon Beom, Lee Hyo Pyo
Abstract excerpt
Cervical cancer is almost invariably associated with infection by human papillomavirus. It is believed that the host genetic factors such as inflammation-induced cytokines may play a role in cervical carcinogenesis. The IL1B gene, encoding IL-1beta cytokine, contains several single nucleotide polymorphisms. One of them which is in the positions -511 (C-T) related with promoter region has been associated with...
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