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Article

Characterization of t(6;11)(p21;q12) in a renal‐cell carcinoma of an adult patient

6 Feb 2007

Abstract excerpt

Renal-cell carcinoma (RCC) constitutes a heterogeneous group of tumors with specific chromosome aberrations. Recently, a new small group of RCC, occurring in children and young adults, has been described as characterized by t(6;11)(p21;q12). It has been shown that this translocation results in the fusion of the 5' portion of the ALPHA gene (11q12) with the transcription factor gene TFEB (6p21). Herewith, we...

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PMID: 17285572
DOI: 10.1002/gcc.20422

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