Article
Histiocyte-rich B-cell lymphoma. A distinct clinicopathologic entity possibly related to lymphocyte predominant Hodgkin's disease, paragranuloma subtype.
The American journal of surgical pathology - 1 Jan 1992
Delabie J, Vandenberghe E, Kennes C, Verhoef G, Foschini M P, Stul M, Cassiman J J, De Wolf-Peeters C
Abstract excerpt
This study reports six non-Hodgkin's lymphoma cases that we called histiocyte-rich B-cell lymphoma (BCL) because of the prominent reactive histiocytic infiltrate obscuring the malignant B-cell population. The involved lymph nodes are characterized by a mixed nodular and diffuse infiltrate and occasionally feature prominent sinuses. The infiltrate is composed of reactive lymphocytes and numerous histiocytes...
Topics
- Adult
- Biopsy
- Bone Marrow
- DNA, Neoplasm
- Gene Rearrangement, B-Lymphocyte, Heavy Chain
- Genotype
- Hodgkin Disease
- Humans
- Immunoglobulins
- Immunohistochemistry
