Article
[Nodular lymphocyte-predominant Hodgkin lymphoma in children: clinical course, biology, and management].
Bulletin du cancer - 1 Sept 2014
Gorde-Grosjean Stéphanie, Guimard Grégory, Lambilliotte Anne, Coulomb-Lhermine Aurore, Montravers Françoise, Landman-Parker Judith
Abstract excerpt
Nodular lymphocyte predominant Hodgkin disease (NLPHL) differs clearly from classical Hodgkin lymphoma (cHL) by clinical presentation and more favorable outcome. Patients often present with early stage IA or IIA. Extranodal disease and B-symptoms are uncommon. Histologically, NLPHL is characterized by the presence of atypical "lymphocyte predominant cells" (LP cells) or "pop-corn" cells in a non-neoplastic and...
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