Article
A novel lux operon in the cryptically bioluminescent fish pathogen Vibrio salmonicida is associated with virulence.
Applied and environmental microbiology - 1 Mar 2007
Nelson Eric J, Tunsjø Hege S, Fidopiastis Pat M, Sørum Henning, Ruby Edward G
Abstract excerpt
The cold-water-fish pathogen Vibrio salmonicida expresses a functional bacterial luciferase but produces insufficient levels of its aliphatic-aldehyde substrate to be detectably luminous in culture. Our goals were to (i) better explain this cryptic bioluminescence phenotype through molecular characterization of the lux operon and (ii) test whether the bioluminescence gene cluster is associated with virulence....
Topics
- Aliivibrio salmonicida
- Amino Acid Sequence
- Animals
- Conserved Sequence
- DNA, Bacterial
- Fish Diseases
- Gadus morhua
- Luciferases, Bacterial
- Molecular Sequence Data
- Mutation
- Operon