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Rotavirus Infection Alters Peripheral T-Cell Homeostasis in Children with Acute Diarrhea

3 Feb 2007

Abstract excerpt

The patterns of gene expression and the phenotypes of lymphocytes in peripheral blood mononuclear cells (PBMC) from children with diarrhea caused by rotavirus and healthy children were compared by using DNA microarray, quantitative PCR, and flow cytometry. We observed increased expression of a number of genes encoding proinflammatory cytokines and interferon or interferon-stimulated proteins and demonstrated...

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PMID: 17267507
DOI: 10.1128/jvi.01887-06

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