Article
Vitamin E succinate inhibits NF-kappaB and prevents the development of a metastatic phenotype in prostate cancer cells: implications for chemoprevention.
The Prostate - 1 May 2007
Crispen Paul L, Uzzo Robert G, Golovine Konstantin, Makhov Peter, Pollack Alan, Horwitz Eric M, Greenberg Richard E, Kolenko Vladimir M
Abstract excerpt
BACKGROUND: NF-kappaB and AP-1 transcriptional factors contribute to the development and progression of prostate malignancy by regulating the expression of genes involved in proliferation, apoptosis, angiogenesis, and metastasis. METHODS: NF-kappaB and AP-1 activities were examined by TransAm ass...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
