Article
Piezotolerant small-colony variants with increased thermotolerance, antibiotic susceptibility, and low invasiveness in a clonal Staphylococcus aureus population.
Applied and environmental microbiology - 1 Mar 2007
Karatzas Kimon A G, Zervos Angelos, Tassou Chrysoula C, Mallidis Costas G, Humphrey Tom J
Abstract excerpt
Following a pressure treatment of a clonal Staphylococcus aureus culture with 400 MPa for 30 min, piezotolerant variants were isolated. Among 21 randomly selected survivors, 9 were piezotolerant and all formed small colonies on several agar media. The majority of the isolates showed increased thermotolerance, impaired growth, and reduced antibiotic resistance compared to the wild type. However, several...
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