Article
Diffuse large B-cell lymphoma arising independently to lymphoplasmacytic lymphoma: a case of two lymphomas.
European journal of haematology - 1 Mar 2007
Sekikawa Tetsuaki, Takahara Shinobu, Suzuki Hideaki, Takeda Nobuakira, Yamada Hisashi, Horiguchi-Yamada Junko
Abstract excerpt
Richter's syndrome occurs in 5-10% of patients with chronic lymphocytic leukemia, either by transformation of the primary neoplastic lymphocyte, or as a distinct B-cell neoplasm. We report a Japanese patient with lymphoplasmacytic lymphoma in whom a diffuse large B-cell lymphoma developed after treatment with rituximab. Molecular examination on immunoglobulin VH genes revealed that the lymphomas had arisen in two...
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