Article
Adrenal involvement in multiple endocrine neoplasia type 1: results of 7 years prospective screening.
Langenbeck's archives of surgery - 1 Jul 2007
Waldmann J, Bartsch D K, Kann P H, Fendrich V, Rothmund M, Langer P
Abstract excerpt
BACKGROUND: Adrenal tumors are a common manifestation of the multiple endocrine neoplasia type 1 (MEN-1) syndrome. Prevalence in recent studies varies between 9 and 45%. A genotype-phenotype correlation has been described as well as the development of adrenocortical carcinomas. Long-term prospective data are still lacking. MATERIALS AND METHODS: Thirty-eight MEN-1 patients with proven germline mutations have been...
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