Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The TNFRSF1A R92Q mutation is frequent in rheumatoid arthritis but shows no evidence for association or linkage with the disease.

Annals of the rheumatic diseases - 1 Aug 2007

Dieudé Philippe, Goossens Michel, Cornélis François, Michou Laëtitia, Bardin Thomas, Tchernitchko Dimitri Olegovitch

Abstract excerpt

OBJECTIVE: TNFRSF1A mutations cause TNFRSF1A-associated periodic syndrome (MIM#142680). A recent study suggested that the R92Q mutation was associated with polyarthritis. We aimed to search for this and other TNFRSF1A mutations in rheumatoid arthritis (RA), and to test for linkage. METHODS: The DNA of 100 trio families and 86 index cases of RA-affected sib-pair (ASP) families from the French Caucasian population...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Linkage Disequilibrium

Share to Mutation

Share to Phenotype

Share to Receptors, Tumor Necrosis Factor, Type I

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 17234651
DOI: 10.1136/ard.2006.060764
PMCID: PMC1954687

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The TNFRSF1A R92Q mutation is frequent in rheumatoid arthritis but shows no evidence for association or linkage with the disease.PMID 17234651Read ↗

Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) in a Dutch family: evidence for a TNFRSF1A mutation with reduced penetrance.Semantic proximity Read ↗

Association between tumor necrosis factor receptor II and familial, but not sporadic, rheumatoid arthritis: evidence for genetic heterogeneity.Semantic proximity Read ↗

A TNFR1 genotype with a protective role in familial rheumatoid arthritis.Semantic proximity Read ↗

Involvement of the same TNFR1 residue in mendelian and multifactorial inflammatory disorders.Semantic proximity Read ↗

Brief Report: The Role of Rare Protein-Coding Variants in Anti-Tumor Necrosis Factor Treatment Response in Rheumatoid Arthritis.Semantic proximity Read ↗

Late-onset tumor necrosis factor receptor-associated periodic syndrome in multiple sclerosis patients carrying the TNFRSF1A R92Q mutation.Semantic proximity Read ↗

Role of tumour necrosis factor (TNF)-α and TNFRSF1A R92Q mutation in the pathogenesis of TNF receptor-associated periodic syndrome and multiple sclerosis.Semantic proximity Read ↗

TNFRSF1A R92Q mutation in association with a multiple sclerosis-like demyelinating syndrome.Semantic proximity Read ↗

Multiple sclerosis and the TNFRSF1A R92Q mutation: clinical characteristics of 21 cases.Semantic proximity Read ↗

Role of the R92Q TNFRSF1A mutation in patients with familial Mediterranean fever.Semantic proximity Read ↗

Long-term clinical profile of children with the low-penetrance R92Q mutation of the TNFRSF1A gene.Semantic proximity Read ↗

TNFRSF1A [corrected] R92Q mutation, autoinflammatory symptoms and multiple sclerosis in a cohort from Argentina.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.