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Article

Expression of a mutant p193/CUL7 molecule confers resistance to MG132- and etoposide-induced apoptosis independent of p53 or Parc binding.

Biochimica et biophysica acta - 1 Mar 2007

Dowell Joshua D, Tsai Shih-Chong, Dias-Santagata Dora C, Nakajima Hidehiro, Wang Zhuo, Zhu Wuqiang, Field Loren J

Abstract excerpt

p193/CUL7 is an E3 ubiquitin ligase initially identified as an SV40 Large T Antigen binding protein. Expression of a dominant interfering variant of mouse p193/CUL7 (designated 1152stop) conferred resistance to MG132- and etoposide-induced apoptosis in U2OS cells. Immune precipitation/Western ana...

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Source

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Identifiers

PMID: 17229476
DOI: 10.1016/j.bbamcr.2006.11.020
PMCID: PMC1876763

Genes

CUL7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17229476-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Expression of a mutant p193/CUL7 molecule confers resistance to MG132- and etoposide-induced apoptosis independent of p53 or Parc binding.PMID 17229476Read ↗

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