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Article

Homocysteine concentrations and molecular analysis in patients with congenital heart defects.

Archives of medical research - 1 Feb 2007

Galdieri Luciano C, Arrieta Santiago R, Silva Célia M C, Pedra Carlos A C, D'Almeida Vânia

Abstract excerpt

BACKGROUND: Congenital heart defects are the result of incomplete heart development and, like many diseases, have been associated with high homocysteine concentration. METHODS: We evaluated homocysteine, folic acid and vitamin B(12) concentrations, and the mutations 677C>T and 1298A>C in MTHFR, 844ins68 in CBS and 2756A>G in MTR genes in 58 patients with congenital heart defects, 38 control subjects, and mothers...

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Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Share to Carbon-Nitrogen Ligases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Cystathionine beta-Synthase

Share to Folic Acid

Share to Heart Defects, Congenital

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Share to Vitamin B 12

Source

Identifiers

PMID: 17227731
DOI: 10.1016/j.arcmed.2006.09.012

Genes

CBS
MTHFR
MTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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