Article
The study of variation in the human genome.
Genomics - 1 Oct 1991
Bowcock A, Cavalli-Sforza L
Abstract excerpt
Regions of the genome showing high evolutionary stability are often conserved as a result of functional constraints. Conversely, more variable regions are likely to represent DNA with no functional or structural importance. However, as in the case of immunologically important regions, sequence divergence does not always indicate lack of functional importance. There is thus a wealth of information from both a...
Topics
- Base Sequence
- DNA Restriction Enzymes
- Demography
- Deoxyribonuclease HpaII
- Deoxyribonucleases, Type II Site-Specific
- Exons
- Genetic Variation
- Genome, Human
- Humans
- Introns
- Molecular Sequence Data
- Multigene Family