Article
Multiplexed SNP typing of ancient DNA clarifies the origin of Andaman mtDNA haplogroups amongst South Asian tribal populations.
PloS one - 20 Dec 2006
Endicott Phillip, Metspalu Mait, Stringer Chris, Macaulay Vincent, Cooper Alan, Sanchez Juan J
Abstract excerpt
The issue of errors in genetic data sets is of growing concern, particularly in population genetics where whole genome mtDNA sequence data is coming under increased scrutiny. Multiplexed PCR reactions, combined with SNP typing, are currently under-exploited in this context, but have the potential to genotype whole populations rapidly and accurately, significantly reducing the amount of errors appearing in...
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