Article
In vitro reactivity of factor VIII inhibitors with von Willebrand factor in different commercial factor VIII concentrates.
American journal of hematology - 1 Jun 2007
Tagariello Giuseppe, Zanotto Daniela, Radossi Paolo, Sartori Roberto, Belvini Donata, Salviato Roberta
Abstract excerpt
A relevant aspect in the treatment of patients with hemophilia A (HA) presenting inhibitor against factor VIII (FVIII) is the different antigenicity of FVIII used for replacement therapy. The aim of the study was to assess the effect of different products, with variable von Willebrand factor (vWF) concentration, in preventing the binding of inhibitor to FVIII. The reactivity of inhibitors from plasma of 18...
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