Article
NPHS1 and NPHS2 gene mutations in Chinese children with sporadic nephrotic syndrome.
Pediatric research - 1 Jan 2007
Mao Jianhua, Zhang Yang, Du Lizhong, Dai Yuwen, Gu Weizhong, Liu Ai'min, Shang Shiqiang, Liang Li
Abstract excerpt
Recent discoveries indicate that the molecules in glomerular podocytes and slit diaphragms may play an important role in the development of proteinuria and nephrotic syndrome. Mutational analyses of NPHS1 and NPHS2 were performed to verify this hypothesis in sporadic nephrotic syndrome (NS) patients. Clinical characteristics and DNA samples were collected from 38 Chinese children with sporadic steroid-sensitive...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.