Article
Rapid genotyping of CTX-M extended-spectrum beta-lactamases by denaturing high-performance liquid chromatography.
Antimicrobial agents and chemotherapy - 1 Apr 2007
Xu Li, Evans Jason, Ling Thomas, Nye Kathy, Hawkey Peter
Abstract excerpt
Denaturing high-performance liquid chromatography (dHPLC) is a powerful technique which has been used extensively to detect genetic variation. This is the first report of the application of dHPLC for rapid genotyping of bacterial beta-lactamase genes. The technique was specifically developed to genotype members of all blaCTX-M DNA homology groups. Thirteen well-defined blaCTX-M extended-spectrum beta-lactamase...
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