Two regions of the tail are necessary for the isoform-specific functions of nonmuscle myosin IIB.

Abstract excerpt

To function in the cell, nonmuscle myosin II molecules assemble into filaments through their C-terminal tails. Because myosin II isoforms most likely assemble into homo-filaments in vivo, it seems that some self-recognition mechanisms of individual myosin II isoforms should exist. Exogenous expression of myosin IIB rod fragment is thus expected to prevent the function of myosin IIB specifically. We expected to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Actins
• Share to Cell Shape
• Share to Cytoskeleton