Article
Co-occurrence of affective and schizophrenia spectrum disorders with PINK1 mutations.
Journal of neurology, neurosurgery, and psychiatry - 1 May 2007
Steinlechner Susanne, Stahlberg Jessica, Völkel Birgit, Djarmati Ana, Hagenah Johann, Hiller Anja, Hedrich Katja, König Inke, Klein Christine, Lencer Rebekka
Abstract excerpt
OBJECTIVE: To investigate a possible association of mutations in the PTEN-induced putative kinase 1 (PINK1) gene with psychiatric disorders in a large family with monogenic parkinsonism. METHOD: 20 members of a family (4 homozygous, 11 heterozygous and 5 non-mutation carriers) were investigated for the presence of psychiatric disorders using the structured clinical interview for Diagnostic and Statistical Manual...
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