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Article

Intracellular distribution of a speech/language disorder associated FOXP2 mutant.

Biochemical and biophysical research communications - 23 Feb 2007

Mizutani Akifumi, Matsuzaki Ayumi, Momoi Mariko Y, Fujita Eriko, Tanabe Yuko, Momoi Takashi

Abstract excerpt

Although a mutation (R553H) in the forkhead box (FOX)P2 gene is associated with speech/language disorder, little is known about the function of FOXP2 or its relevance to this disorder. In the present study, we identify the forkhead nuclear localization domains that contribute to the cellular distribution of FOXP2. Nuclear localization of FOXP2 depended on two distally separated nuclear localization signals in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17196932
DOI: 10.1016/j.bbrc.2006.12.130

Genes

FOXP2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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