The Staphylococcus aureus mec determinant comprises an unusual cluster of direct repeats and codes for a gene product similar to the Escherichia coli sn-glycerophosphoryl diester phosphodiesterase.

doi:10.1128/jb.173.23.7416-7422.1991

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Article

The Staphylococcus aureus mec determinant comprises an unusual cluster of direct repeats and codes for a gene product similar to the Escherichia coli sn-glycerophosphoryl diester phosphodiesterase.

Journal of bacteriology - 1 Dec 1991

Ryffel C, Bucher R, Kayser F H, Berger-Bächi B

Abstract excerpt

The DNA sequence located between mecA, the gene that codes for penicillin-binding protein PBP2', and insertion sequence-like element IS431mec has been termed hypervariable because of its length polymorphism among different staphylococcal isolates. We sequenced and characterized the hypervariable region of the methicillin resistance determinant (mec) isolated from Staphylococcus aureus BB270. Within the 2,040-bp...

Topics

Amino Acid Sequence
Base Sequence
DNA, Bacterial
Escherichia coli
Genes, Bacterial
Genetic Variation
Molecular Sequence Data
Multigene Family
Open Reading Frames
Phosphoric Diester Hydrolases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Plasmids

RNA, Bacterial

Repetitive Sequences, Nucleic Acid

Restriction Mapping

Sequence Homology, Nucleic Acid

Staphylococcus aureus

Source

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Identifiers

PMID: 1718947
DOI: 10.1128/jb.173.23.7416-7422.1991
PMCID: PMC212504

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1718947-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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