Article
The alternative sigma factor sigmaH is required for toxin gene expression by Bacillus anthracis.
Journal of bacteriology - 1 Mar 2007
Hadjifrangiskou Maria, Chen Yahua, Koehler Theresa M
Abstract excerpt
Expression of the structural genes for the anthrax toxin proteins is coordinately controlled by host-related signals, such as elevated CO(2), and the trans-acting positive regulator AtxA. In addition to these requirements, toxin gene expression is under growth phase regulation. The transition state regulator AbrB represses atxA expression to influence toxin synthesis. During the late exponential phase of growth,...
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