Article
Typing of hepatitis C virus genomes by restriction fragment length polymorphism.
The Journal of general virology - 1 Sept 1991
Nakao T, Enomoto N, Takada N, Takada A, Date T
Abstract excerpt
Recently, we reported that hepatitis C virus (HCV) can be classified genetically into two types, HCV-K1 and HCV-K2, which show 67% and 71% identity at the nucleotide and amino acid sequence levels in a 340 bp region which encodes the NS5 gene Gly-Asp-Asp motif. To develop a rapid method to classify the genomes of HCV isolates, we identified restriction fragment length polymorphisms (RFLPs) in reverse...
Topics
- Base Sequence
- DNA, Viral
- Electrophoresis, Polyacrylamide Gel
- Genes, Viral
- Genotype
- Hepacivirus
- Humans
- Molecular Sequence Data
- Nucleic Acid Hybridization
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length