Article
Efficacy and safety of Helicobacter pylori eradication therapy with omeprazole, amoxicillin and high- and low-dose clarithromycin in Japanese patients: a randomised, double-blind, multicentre study.
Clinical drug investigation - 1 Jan 2006
Higuchi Kazuhide, Maekawa Takama, Nakagawa Koichiro, Chouno Shinji, Hayakumo Takanobu, Tomono Naomi, Orino Akio, Tanimura Hirohisa, Asahina Kan, Matsuura Naotaka, Endo Motohiko, Hirano Masanori, Sakamoto Choitsu, Inomoto Tsutomu, Arakawa Tetsuo
Abstract excerpt
OBJECTIVE: Seven-day administration of omeprazole 40 mg/day + amoxicillin 1500 mg/day + clarithromycin 800 mg/day is currently approved in Japan for the eradication of Helicobacter pylori infection. We investigated the efficacy and safety of an omeprazole-based triple therapy regimen in combination with amoxicillin and low-dose clarithromycin in Japanese patients. METHODS: Patients were randomly assigned to...
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