Article
Secreted factors from ventral telencephalon induce the differentiation of GABAergic neurons in cortical cultures.
The European journal of neuroscience - 1 Dec 2006
Trinh H-h, Reid J, Shin E, Liapi A, Parnavelas J G, Nadarajah B
Abstract excerpt
It is widely believed that the pyramidal cells and interneurons of the cerebral cortex are distinct in their origin, lineage and genetic make up. In view of these findings, the current thesis is that the phenotype determination of cortical neurons is primarily directed by genetic mechanisms. Using in vitro assays, the present study demonstrates that secreted factors from ganglionic eminence (GE) of the ventral...
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