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Article

Generalized progressive retinal atrophy of Sloughi dogs is due to an 8-bp insertion in exon 21 of the PDE6B gene.

Cytogenetics and cell genetics - 1 Jan 2000

Dekomien G, Runte M, Gödde R, Epplen J T

Abstract excerpt

We investigated the gene encoding the beta subunit of cGMP phosphodiesterase (PDE6B) as a candidate for generalized progressive retinal atrophy (gPRA), an autosomal recessively transmitted eye disease in dogs. The PDE6B gene was isolated from a genomic library. Single-strand conformation polymorp...

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Share to 3',5'-Cyclic-GMP Phosphodiesterases
Share to Cyclic Nucleotide Phosphodiesterases, Type 6
Share to Dog Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutagenesis, Insertional

Share to Polymorphism, Single-Stranded Conformational

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Share to Retinal Degeneration

Source

Identifiers

PMID: 11124530
DOI: 10.1159/000056785

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11124530-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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