Article
Rheumatoid arthritis association with the FCRL3 -169C polymorphism is restricted to PTPN22 1858T-homozygous individuals in a Canadian population.
Arthritis and rheumatism - 1 Dec 2006
Newman William G, Zhang Qing, Liu Xiangdong, Walker Erin, Ternan Heather, Owen Julie, Johnson Ben, Greer Wenda, Mosher Dianne P, Maksymowych Walter P, Bykerk Vivian P, Keystone Edward C, Amos Christopher I, Siminovitch Katherine A
Abstract excerpt
OBJECTIVE: Variants in genes encoding the Fc receptor-like 3 (FcRL-3) and the class II major histocompatibility complex (MHC) transactivator proteins have been associated with an increased risk of rheumatoid arthritis (RA) in Japanese and Nordic populations, respectively. The aim of this study was to investigate these associations in a Canadian Caucasian cohort of RA cases and healthy controls. METHODS: A total...
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