Article
The relationship of target organ damage and 24-hour ambulatory blood pressure monitoring with vitamin D receptor gene fok-I polymorphism in essential hypertension.
Kidney & blood pressure research - 1 Jan 2006
Kulah Eyup, Dursun Ahmet, Acikgoz Serefden, Can Murat, Kargi Sebnem, Ilikhan Sevil, Bozdogan Sevcan
Abstract excerpt
BACKGROUND: The contribution of genetic factors in hypertension cannot be denied. METHODS: In this study we evaluated the relationship between vitamin D receptor (VDR) gene polymorphisms (Bsm-I, Apa-I and Fok-I), and target organ damage in 74 patients (female/male 49/25, mean age 49.2 +/- 8 years) with essential hypertension. The VDR genotypes were evaluated by polymerase chain reaction and digestion of the...
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