Article
MHC class II genes in Mexican patients with idiopathic dilated cardiomyopathy.
Experimental and molecular pathology - 1 Feb 2007
Rodríguez-Pérez José Manuel, Fragoso José Manuel, Alvarez-León Edith, Martínez-Rodríguez Nancy, Gallardo Guillermo J, Inés-Real Selene, Granados Julio, Reyes Pedro A, Vargas-Alarcón Gilberto
Abstract excerpt
The purpose of the present study was to evaluate the relationship between class II major histocompatibility complex (MHC) genes (HLA-DR and HLA-DQB) and the genetic susceptibility to idiopathic dilated cardiomyopathy (IDC) in Mexican patients. The HLA-DR and DQB alleles were analyzed in 53 patients with IDC and 99 ethnically matched healthy controls using the polymerase chain reaction-sequence specific...
Topics
- Cardiomyopathy, Dilated
- Genes, MHC Class II
- Genetic Predisposition to Disease
- Humans
- Mexico
- Polymerase Chain Reaction