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Article

Pharmacogenetics-based coumarin therapy.

Hematology. American Society of Hematology. Education Program - 1 Jan 2006

Gage Brian F

Abstract excerpt

To reduce the risk of hemorrhage, experts advocate prescribing the anticipated therapeutic dose to patients who are beginning coumarin therapy, but until now there was no accurate way to estimate that dose. Using pharmacogenetics-based coumarin therapy, clinicians can now estimate the therapeutic dose by genotyping their patients for single nucleotide polymorphisms (SNPs) that affect coumarin metabolism or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aryl Hydrocarbon Hydroxylases

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Share to Cytochrome P-450 CYP2C9

Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 17124101
DOI: 10.1182/asheducation-2006.1.467

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Pharmacogenetics-based coumarin therapy.PMID 17124101Read ↗

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