Article
Computational studies for the structure and function of mRPE65.
Journal of theoretical biology - 21 Mar 2007
Guo Hao, Zheng Chong, Gaillard Elizabeth R
Abstract excerpt
The mRPE65 protein is one form of the RPE65 protein and plays a very important role in the visual cycle. However, its 3D structure and detailed mechanism of function are still unclear because of difficulties with isolation and crystallization. This computational study reports a model for the mRPE65 protein structure derived from a model for sRPE65. The natural substrate for RPE65 has been shown to be a retinyl...
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