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Article

Antisense transcription controls cell fate in Saccharomyces cerevisiae.

Cell - 17 Nov 2006

Hongay Cintia F, Grisafi Paula L, Galitski Timothy, Fink Gerald R

Abstract excerpt

Entry into meiosis is a key developmental decision. We show here that meiotic entry in Saccharomyces cerevisiae is controlled by antisense-mediated regulation of IME4, a gene required for initiating meiosis. In MAT a/alpha diploids the antisense IME4 transcript is repressed by binding of the a1/alpha2 heterodimer at a conserved site located downstream of the IME4 coding sequence. MAT a/alpha diploids that produce...

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Identifiers

PMID: 17110333
DOI: 10.1016/j.cell.2006.09.038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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